Biochem/physiol Actions LY320135 is a potent CB1 receptor antagonist/inverse agonist (Ki = 141 nM) with greater than 70-fold selectivity over CB2 receptors (Ki >: 10 μ:M). Structurally dissimilar from SR 141716A and AM 251.
Biochem/physiol Actions LY320135 is a potent CB1 receptor antagonist/inverse agonist (Ki = 141 nM) with greater than 70-fold selectivity over CB2 receptors (Ki >: 10 μ:M). Structurally dissimilar from SR 141716A and AM 251.
Biochem/physiol Actions LY2603618 (LCI-1) is a potent and selective checkpoint kinase 1 (Chk1) inhibitor (IC 50 = 7 nM) that produces a cellular phenotype identical to that reported upon Chk1 depletion by RNAi. LY2603618 prevents
Biochem/physiol Actions LY2603618 (LCI-1) is a potent and selective checkpoint kinase 1 (Chk1) inhibitor (IC 50 = 7 nM) that produces a cellular phenotype identical to that reported upon Chk1 depletion by RNAi. LY2603618 prevents
Biochem/physiol Actions LY2603618 (LCI-1) is a potent and selective checkpoint kinase 1 (Chk1) inhibitor (IC 50 = 7 nM) that produces a cellular phenotype identical to that reported upon Chk1 depletion by RNAi. LY2603618 prevents
Biochem/physiol Actions LY2603618 (LCI-1) is a potent and selective checkpoint kinase 1 (Chk1) inhibitor (IC 50 = 7 nM) that produces a cellular phenotype identical to that reported upon Chk1 depletion by RNAi. LY2603618 prevents
Biochem/physiol Actions LY2828360 is a potent and selective slowly acting G protein-biased CB2 cannabinoid agonist that inhibits cAMP accumulation and activates ERK1/2 signaling while failing to recruit arrestin. LY2828360 suppress
Biochem/physiol Actions LY2828360 is a potent and selective slowly acting G protein-biased CB2 cannabinoid agonist that inhibits cAMP accumulation and activates ERK1/2 signaling while failing to recruit arrestin. LY2828360 suppress
Biochem/physiol Actions LY2828360 is a potent and selective slowly acting G protein-biased CB2 cannabinoid agonist that inhibits cAMP accumulation and activates ERK1/2 signaling while failing to recruit arrestin. LY2828360 suppress
Biochem/physiol Actions LY2828360 is a potent and selective slowly acting G protein-biased CB2 cannabinoid agonist that inhibits cAMP accumulation and activates ERK1/2 signaling while failing to recruit arrestin. LY2828360 suppress