Kisspeptin-10, human TFA is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development.Appearance:SolidIC50& Target:GPR54 AngiogenesisIn Vitro:Kisspeptin-10 (KP-10) and its receptor GPR54 are key components in the regulation of GnRH secretion in humans and other mammals. Kisspeptin-10 protein binds to GPR54. Activation of Kisspeptin-10 suppresses pulmonary human melanoma and Kisspeptin-10 is a mIn Vivo:Intravenous infusion of kisspeptin-10 (7.5, 35, and 100 nM) induces a dose-dependent increase in LH secretion. The stimulatory effect of kisspeptin-10 (100 n nM) on LH secretion is blocked by the GnRH antagonist cetrorelix, precluding a singular action onBiological Activity:Kisspeptin-10, human TFA is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development.
Specifications and Purity: ≥98%
Molecular Formula: C63H83N17O14.C2HF3O2
Molecular Weight: 1416.46
- UPC:
- 51142508
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- K659446-5mg
- Product Size:
- 5mg
akash.verma@cenmed.com
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