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Biochem/physiol Actions NAMI-A is a potent antimetastatic drug in vivo that is exhibits little cytotoxicity towards many cancer cell lines. Antimetastatic of NAMI-A is attributed to the formation of adducts with membrane and cytosolic proteins.

Application STA-21 has been used as a signal transducer and activator of transcription 3 (STAT3) inhibitor to study its effects on glioblastoma and primary glioblastoma cells. It has also been used as a STAT3 dimerization inhibitor to study its

Application STA-21 has been used as a signal transducer and activator of transcription 3 (STAT3) inhibitor to study its effects on glioblastoma and primary glioblastoma cells. It has also been used as a STAT3 dimerization inhibitor to study its

Biochem/physiol Actions ABC99 is an N-hydroxyhydantoin (NHH) carbamate-based irreversible, potent and selective inhibitor against the serine hydrolase activity of the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM against NOTUM-mediated labeling of

Biochem/physiol Actions ABC99 is an N-hydroxyhydantoin (NHH) carbamate-based irreversible, potent and selective inhibitor against the serine hydrolase activity of the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM against NOTUM-mediated labeling of

Biochem/physiol Actions M090 is a potent inhibitor of influenza A hemagglutinin that is effective against amantadine-resistant and oseltamivir-resistant viruses.

Biochem/physiol Actions M090 is a potent inhibitor of influenza A hemagglutinin that is effective against amantadine-resistant and oseltamivir-resistant viruses.

Biochem/physiol Actions CINPA1 is a ligand-binding domain (LBD)-targeting constitutive androstane receptor (CAR) inhibitor that prevents CAR recruitment to promoter regions of regulated genes (by &gt:85%: 1 &#956:M CINPA1 against 0.1 &#956:M

Biochem/physiol Actions CINPA1 is a ligand-binding domain (LBD)-targeting constitutive androstane receptor (CAR) inhibitor that prevents CAR recruitment to promoter regions of regulated genes (by &gt:85%: 1 &#956:M CINPA1 against 0.1 &#956:M

Biochem/physiol Actions BDT001 is a selective negative allosteric modulator of Flt-3 receptor tyrosine kinase. It showed minimal binding to 25 diverse RTKs and 49 intracellular kinases.

Biochem/physiol Actions BDT001 is a selective negative allosteric modulator of Flt-3 receptor tyrosine kinase. It showed minimal binding to 25 diverse RTKs and 49 intracellular kinases.

Biochem/physiol Actions LHVS is an irreversible, potent and selective cathepsin S inhibitor (CatS Ki = 5.9 nM: CatO2/L/B Ki = 0.