Lepirudin

LTB3 is the LTA hydrolase metabolite of LTA3 in the leukotriene biosynthetic pathway. LTB3 and LTB4 are equipotent in their pro-inflammatory effects. However, LTB3 is five times less potent than LTB4 in eliciting chemotaxis of human neutrophils.

A bioactive sterol that can affect cholesterol homeostasis, membrane properties and cell survival inhibits CYP7A1 with an IC₅₀ = ~ 1 &microM can be used as a standard in the determination of cholesterol derivatives by GC-MS or HPLC.

A reversible inhibitor of cysteine, serine, and threonine proteases inhibits cathepsin B (Ki = 6 nM), calpain (Ki = 10 nM), trypsin (Ki = 35 nM), plasmin (Ki = 3.4 &muM), and kallikrein (Ki = 19 &muM), and has no effect against chymotrypsin,

A selective SGLT2 inhibitor (IC₅₀ = 3.1 nM) that has been shown in clinical trials of patients with type 2 diabetes to lower fasting and postprandial glucose levels by increasing total glucose excretion, improving &beta-cell function,

Immunogen: synthetic peptide from the N-terminal region of human H-PGDS Host: rabbit Species Reactivity: (+) human, baboon, mouse, and rat H-PGDS Application(s): WB

A major flavonolignan from the extracts of milk thistle seed, S. marianum blocks the production of superoxide in PMA-activated rat Kupffer cells (EC50 = ~100 &microM) inhibits the synthesis of LTB4 (IC50 = ~15 &microM).

A potent, competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM).

A flavonoid originally isolated from the roots of Scutellaria baicalensis Georg inhibits platelet 12-LO with an ID50 value of 0.12 &microM, with minimal inhibition of platelet COX-1 (IC₅₀ = 0.

Sleeve 0.25in Dia Black on White 0.75in

Hirudin: Hirudin is a potent thrombin inhibitor originally derived from the medicinal leech Unlike heparin, hirudin act directly on thrombin, rather than through other clotting factors. They have a high binding affinity and specificity for thrombin.

Leptin, human: Human Leptin plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones.

Anti-LUZP6 leucine zipper protein 6, 100ul UN 1687 6.1 PG2