akash.verma@cenmed.com
(732) 447-1115-
14870-10A potent, allosteric inhibitor of Akt1 and Akt2 (IC<sub>50</sub> = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC<sub>50</sub> = 2.2 µM) cell permeable, blocking insulin regulation of FOXO1 activity at 1 µM -
17132-5An orally bioavailable antagonist of the androgen receptor (IC<sub>50</sub> = 16 nM) at 30 mg/kg/d, suppresses tumor growth in a mouse model of castration-resistant prostate cancer. -
17150-25A peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. -
18129-25An orally bioavailable inhibitor of ACAT (IC<sub>50</sub>s = 24 and 9.2 µM for ACAT1 and ACAT2, respectively) that reduces plasma total triglyceride and VLDL cholesterol levels in cholesterol-fed animal models also used to decrease amyloid -
18506-5An aminopeptidase B inhibitor that is commonly used to characterize novel proteases. -
18604-10A cell-permeable, copper-containing 3-formylchromone derivative that inhibits Akt in an array of cancer cells (IC<sub>50</sub>s = 10-34 µM) also causes NF-&kappaB inactivation in an orthotopic pancreatic tumor model using COLO 357 cells. -
360013-200Peptide Sequence: human hematopoietic type PGD synthase amino acids 30-41 (EDHRIEQADWPE) To be used in conjunction with Cayman&rsquos hematopoietic type PGD synthase polyclonal antibody (Catalog No. 160013) to block protein-antibody complex -
10498-10A selective, reversible inhibitor of autotaxin, completely blocking the hydrolysis of the substrate bis-pNPP with an IC50 value of 28 nM rapidly decreases plasma lysophosphatidic acid levels in mice when given intravenously (1 nM/g). -
14870-5A potent, allosteric inhibitor of Akt1 and Akt2 (IC<sub>50</sub> = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC<sub>50</sub> = 2.2 µM) cell permeable, blocking insulin regulation of FOXO1 activity at 1 µM -
17119-5A benzoxazolone carboxamide that potently inhibits acid ceramidase (IC<sub>50</sub> = 79 nM) extremely stable in buffers and plasma and shows good pharmacokinetics when administered intravenously or intraperitoneally in mice, significantly reducing -
17150-10A peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. -
16933-10A broad-spectrum, indole-based antiviral compound that blocks viral fusion with target membranes, prohibiting viral entry into cells effective against numerous viruses, including influenza A, B, and C and hepatitis B and C (IC<sub>50</sub>s range
