Famotidine

A cell-permeable benzamide compound that acts as an effective inhibitor against RhoA- and RhoC-mediated cellular activities by targeting signaling events downstream of G&#945 12/13 and RhoA/C, affecting MKL recruitment and/or postrecruitment

A cell-permeable trisubstituted thiazole compound that acts as a potent and selective inhibitor of COX-1 (IC 50 = 28 nM and 65 &#181M for human recombinant COX-1 and COX-2, respectively). Displays ~2,300 fold greater selectivity towards inhibition

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the

A cell-permeable sulfonamide compound that acts as a dual pathway inhibitor against Wnt/&#946-catenin (&#880580% inhibition at 15 &#181M in &#946-catenin/Tcf-dependent cellular reporter assays) and PPAR&#947/&#948 (&#880530% inhibition at