Difenidol or diphenidol

The major metabolite formed during the metabolism of the non-steroidal antiandrogen flutamide by cytochrome P450 isoforms CYP1A2 and CYP3A4 inhibits the binding of testosterone to the nuclear androgen receptor (IC₅₀ = ~300-900), blocking

An inhibitor of SAH hydrolase (Ki = 3.9 &muM) has anti-inflammatory, anti-viral, and anti-bacterial activities.

A glutamine analog that inhibits glutaminases (Ki = 6 &microM) and other glutamine-utilizing enzymes, including cytidine triphosphate synthase.

A stable, monomethoxylated resveratrol derivative that at 0.1-10 &muM reduces neurotoxicity in SH-SY5Y cells induced by the parkinsonian mimetic 6-OHDA and scavenges DPPH radicals (IC₅₀ = 47.1 &muM).

A fluorogenic probe that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19) used to detect changes in CYP catalytic activity caused by drugs or disease.

A non-selective mACh receptor antagonist and non-specific inhibitor of voltage-gated ion channels in neurons used to study animal models of vertigo and emesis.

A small molecule, multi-targeted receptor tyrosine kinase inhibitor blocks the autophosphorylation of both wild type and mutant forms of Kit in response to stem cell factor, resulting in cell death active in vivo and commonly used against solid

A competitive antagonist of muscarinic receptors that potently blocks signaling through M1, M2, and M3 (Kis = 25, 125, and 10 nM, respectively), resulting in muscle relaxation.

A third generation, irreversible steroidal aromatase inhibitor (Ki = 10.2 nM Kinact = 26 nM) that induces aromatase degradation, which leads to a decrease in estrogen levels in plasma.

An anti-epileptic drug that inhibits the synaptosomal uptake of GABA, increasing the activation of GABAA receptors inhibits CYP3A4, CYP1A2, and CYP2C19 inhibits LDH, blocking both lactate-to-pyruvate and pyruvate-to-lactate conversions by human

A natural iridoid glycoside that blocks changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver also enhances neurite outgrowth in PC12D cells induced by bFGF and 7S NGF when

A stable, monomethoxylated resveratrol derivative that at 0.1-10 &muM reduces neurotoxicity in SH-SY5Y cells induced by the parkinsonian mimetic 6-OHDA and scavenges DPPH radicals (IC₅₀ = 47.1 &muM).