A fluorogenic probe that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19) used to detect changes in CYP catalytic activity caused by drugs or disease.
A fluorogenic probe that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19) used to detect changes in CYP catalytic activity caused by drugs or disease.
An anti-epileptic drug that inhibits the synaptosomal uptake of GABA, increasing the activation of GABAA receptors inhibits CYP3A4, CYP1A2, and CYP2C19 inhibits LDH, blocking both lactate-to-pyruvate and pyruvate-to-lactate conversions by human
An anti-epileptic drug that inhibits the synaptosomal uptake of GABA, increasing the activation of GABAA receptors inhibits CYP3A4, CYP1A2, and CYP2C19 inhibits LDH, blocking both lactate-to-pyruvate and pyruvate-to-lactate conversions by human
A stable, monomethoxylated resveratrol derivative that at 0.1-10 &muM reduces neurotoxicity in SH-SY5Y cells induced by the parkinsonian mimetic 6-OHDA and scavenges DPPH radicals (IC<sub>50</sub> = 47.1 &muM).
A stable, monomethoxylated resveratrol derivative that at 0.1-10 &muM reduces neurotoxicity in SH-SY5Y cells induced by the parkinsonian mimetic 6-OHDA and scavenges DPPH radicals (IC<sub>50</sub> = 47.1 &muM).
A non-selective mACh receptor antagonist and non-specific inhibitor of voltage-gated ion channels in neurons used to study animal models of vertigo and emesis.
A non-selective mACh receptor antagonist and non-specific inhibitor of voltage-gated ion channels in neurons used to study animal models of vertigo and emesis.
An anti-epileptic drug that inhibits the synaptosomal uptake of GABA, increasing the activation of GABAA receptors inhibits CYP3A4, CYP1A2, and CYP2C19 inhibits LDH, blocking both lactate-to-pyruvate and pyruvate-to-lactate conversions by human
An anti-epileptic drug that inhibits the synaptosomal uptake of GABA, increasing the activation of GABAA receptors inhibits CYP3A4, CYP1A2, and CYP2C19 inhibits LDH, blocking both lactate-to-pyruvate and pyruvate-to-lactate conversions by human