Latanoprost

Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E).

An analog of latanoprost in which the hydroxyl at C-15 is inverted relative to latanoprost binds to the FP receptor in the cat iris sphincter muscle with an IC₅₀ value of 24 &microM (tested as the free acid) potential impurity in

Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro PGF2&alpha. It is a prodrug form of the free acid, which is a potent agonist of the FP receptor in the eye.

Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Latanoprost lactone diol is an intermediate in the synthesis of latanoprost.

A potential metabolite of latanoprost when administered to animals common minor impurity found in commercial preparations of the bulk drug compound.

An analog of latanoprost in which the hydroxyl at C-15 is inverted relative to latanoprost binds to the FP receptor in the cat iris sphincter muscle with an IC₅₀ value of 24 &microM (tested as the free acid) potential impurity in

An internal standard for the quantification of latanoprost (free acid) by GC- or LC-MS.

An internal standard for the quantification of Latanoprost by GC- or LC-MS.

A potential metabolite of latanoprost when administered to animals.

An isomer of latanoprost (free acid) wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E) intended primarily as an analytical standard.

Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity.

Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E).