Risperidone

A potent antagonist of dopamine receptors (IC₅₀s = 1.0 and 0.

An Axl kinase inhibitor.

A potent antagonist of the TXA2 receptor, blocking specific binding of U-46619 to platelets with an IC₅₀ value of 7.4 nM and platelet aggregation induced by U-44069 with an IC₅₀ value of 350 nM commonly used to study the roles

A long-lasting rifamycin antibiotic that is effective against Mycobacterium species, including M. tuberculosis as well as experimental infections caused by S. aureus, S. pyogenes group A, S. pneumoniae, and K. pneumoniae.

An antibiotic derived from rifamycin that targets most Gram-positive and Gram-negative bacteria poorly absorbed after oral administration effective in eliminating bacteria in the gastrointestinal system.

An inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 &muM, respectively, with Poly(dI-dC) as the substrate) reactivates silenced tumor suppressor genes by reducing CpG island hypermethylation.

Acts as a partial agonist at the 5-HT1A receptor (pKi = 7) and interferes to a lesser extent with the binding of dopamine at D1, D2, D3 and D5 receptors, yet has a high affinity for the D4 receptor.

An antipsychotic, thienobenzodiazepine compound that binds as an antagonist/inverse agonist to dopamine D1 (Ki = 31 nM), dopamine D2 (Ki = 11 nM), dopamine D4 (Ki = 27 nM), serotonin 5-HT2A (Ki = 4 nM), serotonin 5-HT2C (Ki = 11 nM), serotonin 5-HT3

An antibiotic derived from rifamycin that targets most Gram-positive and Gram-negative bacteria poorly absorbed after oral administration effective in eliminating bacteria in the gastrointestinal system.

Molecular Formula: C₁₇H₁₂N₂O₂ Formula Weight: 276.3

A stable analog of 2-PG bearing an amide linkage in place of the labile glyceryl ester which endows it with a prolonged in vivo half-life also an analog of C-16 ceramide causes apoptosis (IC₅₀ = 80 &microM) when incubated with

A potent antagonist of dopamine receptors (IC₅₀s = 1.0 and 0.