Carbidopa

AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively. In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161

An alkaloid originally found to have antimicrobial actions both 5-LO and COX-2 (IC₅₀s = 600 and 64 nM, respectively) suppresses angiogenesis, blocking signaling through VEGFR2 at the level of ERK1/2 signaling prevents ERK signaling

Molecular Formula: C₂₈H₂₄F₃N₇O₂

An inhibitor of PD-1/PD-L1 interaction.

GDC-0623 is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki = 0.13 nM in the presence of ATP).

One of the phenolic antioxidants present in extracts of rosemary inhibits the formation of tumors derived using irritants such as TPA and DMBA.

A protopanaxadiol that has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions.

A protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions.

Prevents the interaction of PD-L1 with PD-1 with an IC₅₀ value of 18 nM.

An indole plant alkaloid used as a peripheral vasodilator to increase blood flow to the brain contracts excised human cerebrovascular smooth muscle in vitro with an EC50 value of 30 &muM.

A mycotoxin which is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 &muM induces apoptosis in mammalian cells with an IC50 value of 4.5 &muM.

Carbaprostacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex vivo platelet aggregation, but the effect persists only 10 minutes after termination of the infusion.