Carbidopa

A potent pan inhibitor of class I catalytic subunits of PI3K, inhibiting p110&alpha, &beta, &delta, and &gamma with IC50 values of 3, 33, 3, and 75 nM, respectively inhibits the growth of certain types of cancer cells, and blocks signaling

A structural analog of NAADP that blocks NAADP-dependent calcium release (IC₅₀ = 6 nM) as well as NAADP binding to sea urchin egg homogenate (IC₅₀ = 0.4 nM) does not affect either IP3-mediated calcium release or cyclic

Prevents the interaction of PD-L1 with PD-1 with an IC₅₀ value of 18 nM.

A mycotoxin which is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 &muM induces apoptosis in mammalian cells with an IC50 value of 4.5 &muM.

An affinity probe which allows carbaprostacyclin to be detected in complexes with transmembrane receptors and/or nucleic or protein binding partners.

A natural glycoinsolate found in cruciferous vegetables, including broccoli converted to the isothiocyanate sulforaphane by the enzyme myrosinase, resulting in antioxidant, anti-inflammatory, and anti-carcinogenic effects.

An allosteric inhibitor of oncogenic K-Ras(G12C).

An analog of L-carnitine that, in the range of 0.25-1 mM, inhibits the uptake of L-carnitine by cells.

An analog of cyclopamine that inhibits the Hh signaling-dependent proliferation of NIH/3T3 cells at 8 &muM and dose dependently inhibits platelet aggregation in rabbits ex vivo induces serotonin release and inhibits its re-uptake in the CNS.

A protopanaxatriol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-diabetic actions protects against DNA damage and apoptosis induced by ultraviolet light.

An intermediate aldehyde metabolite of losartan that does not block angiotensin receptors, but instead inhibits COX-2 expression, blocks ICAM-1 mRNA upregulation, and COX-dependent generation of TXA2 and PGF2&alpha also acts as a partial agonist

A natural 3-O-galactoside of quercetin that has powerful antioxidant action through its ability to scavenge free radicals (IC₅₀s = 3.54 and 5.44 &microg/ml in ABTS and DPPH assays, respectively).