Leuprolide

LTD4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by &gamma-glutamyl transpeptidase. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the

A theoretical 5-LO metabolite of AEA acts as a potent antagonist of the human BLT1 receptor (Ki = 1.22 nM).

An initial metabolite of LTB4 with significantly reduced biological activity.

LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL. LTB4 dimethyl amide appears to be an antagonist of the LTB4 receptor on guinea pig lung membranes.

12-epi Leukotriene B4-d4 (12-epi LTB4-d4) contains four deuterium atoms at the 6, 7, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 12-epi LTB4 by GC- or LC-mass spectrometry.

An AEA transport inhibitor with essentially no activity on the CB1 receptor, CB2 receptor, or TRPV1 inhibits FAAH and MAGL and may act as an alternative FAAH substrate inhibits glutamergic synaptic transmission between hippocampal neurons at a

Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans LTE4 is equipotent to LTE4 in contracting guinea pig ileum.

11-trans LTD4 is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage.

11-trans LTC4 is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage.

Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and

An internal standard for the quantification of LTA4 methyl ester by GC- or LC-MS.

An intermediate for the synthesis of carbohydrates.