Leuprolide

12-epi Leukotriene B4-d4 (12-epi LTB4-d4) contains four deuterium atoms at the 6, 7, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 12-epi LTB4 by GC- or LC-mass spectrometry.

Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans LTE4 is equipotent to LTE4 in contracting guinea pig ileum.

11-trans LTD4 is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage.

A metabolite of LTB4 in human neutrophils inhibits LTB4-induced degranulation of human neutrophilis (Ki = 13.3 nM).

An internal standard for the quantification of LTD4 by GC- or LC-MS.

An internal standard for the quantification of LTC4 by GC- or LC-MS.

An internal standard for the quantification of LTE4 by GC- or LC-MS.

Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and

An internal standard for the quantification of LTC4 methyl ester by GC- or LC-MS.

An internal standard for the quantification of LTA4 methyl ester by GC- or LC-MS.

A phenol product produced by the reaction of H₂O₂with the ratiometric MS probe MitoB quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H₂O₂ concentration.

The parent CysLT produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4 potent inducer of bronchoconstriction and enhanced vascular permeability that contributes to the pathogenesis of asthma and acute allergic hypersensitivity.