Bicalutamide

The RPI methyl-a-D-mannopyranoside with strong concentration levels should always be stored in a temperature of 2 to 8 degree C and is used in research and manufacturing applications. Application: For Research or Further Manufacturing use only

The RPI methyl-a-D-mannopyranoside with strong concentration levels should always be stored in a temperature of 2 to 8 degree C and is used in research and manufacturing applications. Application: For Research or Further Manufacturing use only

4-Methylumbelliferyl-N- acetyl-&beta-D- galactoside 4-Methylumbelliferyl-2-acetamido-2-deoxy-beta-D-galactopyranoside 4-MU-beta-D-GalNAc &nbsp MOLECULAR BIOLOGY GRADE &nbsp White to off white powder &nbsp Fluorogenic substrate for

Bisindolylmaleimide IV CAS 119139-23-0 Calbiochem 1MG

A cell permeable inhibitor of PKC with IC₅₀ values reported to range from 0.10 to 0.

An antagonist of the &alpha3&beta4 nicotinic acetylcholine receptor subtype (IC50 = 10.2 &muM) selectively binds the &alpha3&beta4 subtype, compared to the &alpha4&beta2 and &alpha7 subtypes (Ki values of 0.

Inhibitor of NF-&kappaB activation that blocks the phosphorylation of IKK and I&kappaB (IC50 ~ 40 &muM) dose dependently inhibits the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.

A reversible, selective, allosteric antagonist of mGluR7 that blocks agonist-induced calcium mobilization (IC₅₀ = 26 nM).

A highly selective, cell-permeable, and reversible PKC inhibitor (Ki = 14 nM) acts as a competitive inhibitor for the ATP binding site of PKC and shows high selectivity for PKC&alpha-, &beta1-, &beta2-, &gamma-, &delta-, and

A weak inhibitor of PKC demonstrating an IC₅₀ value &gt100 &microM blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC₅₀ value of 8 &microM.

A derivative of GABA that acts as an antagonist of GABAA receptors (Ki = 74-150 nM) elicits seizures when administered intravenously in mice effective against GABAA receptor isoforms from mice, rats, and humans.

A selective, positive allosteric modulator of mGluR2, stimulating the human and rat receptors with EC50 values of 33.2 and 96 nM, respectively can be used on cells, tissues, or animals.