A CoA derivative used in fatty acid and polyketide synthesis and in the transport of &alpha-ketoglutarate across the mitochondrial membrane may mediate cancer cell cytotoxicity induced by fatty acid synthase inhibition.
A CoA derivative used in fatty acid and polyketide synthesis and in the transport of &alpha-ketoglutarate across the mitochondrial membrane may mediate cancer cell cytotoxicity induced by fatty acid synthase inhibition.
A natural antitumor inhibitor of cell adhesion to extracellular matrix that potently and selectively inhibits PP2A (IC<sub>50</sub> = 29 nM against the catalytic subunit), while having no effect against PP1, PP2B, or PP5.
A natural antitumor inhibitor of cell adhesion to extracellular matrix that potently and selectively inhibits PP2A (IC<sub>50</sub> = 29 nM against the catalytic subunit), while having no effect against PP1, PP2B, or PP5.
A &beta-lactam antibiotic that lyses actively-growing E. coli by binding specifically to penicillin-binding proteins 1a and b whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.
A &beta-lactam antibiotic that lyses actively-growing E. coli by binding specifically to penicillin-binding proteins 1a and b whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.
An intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi metabolized by a variety of enzymes in mammals, including N-acetyltransferases may also be utilized by bacteria or fungi that
An intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi metabolized by a variety of enzymes in mammals, including N-acetyltransferases may also be utilized by bacteria or fungi that
The oxidized form of GSH that can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation
The oxidized form of GSH that can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation
A &beta-lactam antibiotic that lyses actively-growing E. coli by binding specifically to penicillin-binding proteins 1a and b whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.
A &beta-lactam antibiotic that lyses actively-growing E. coli by binding specifically to penicillin-binding proteins 1a and b whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.
A potent, non-ATP-competitive inhibitor of Plk1 (IC<sub>50</sub> = 9 nM) induces apoptosis in a wide array of tumor cell lines (GI50 = 50-200 nM) active in vivo when administered intraperitoneally and synergizes with chemotherapeutic agents.
A potent, non-ATP-competitive inhibitor of Plk1 (IC<sub>50</sub> = 9 nM) induces apoptosis in a wide array of tumor cell lines (GI50 = 50-200 nM) active in vivo when administered intraperitoneally and synergizes with chemotherapeutic agents.
The oxidized form of GSH that can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation
The oxidized form of GSH that can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation
An intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi metabolized by a variety of enzymes in mammals, including N-acetyltransferases may also be utilized by bacteria or fungi that
An intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi metabolized by a variety of enzymes in mammals, including N-acetyltransferases may also be utilized by bacteria or fungi that