InformationSpironolactone Spironolactone is a potent antagonist of the androgen receptor with IC50 of 77 nM.In vitroSpironolactone is a strong AR antagonist (IC50 ~ 77 nM), a weak GR antagonist (IC50 ~ 2.4 μM), and a weak PR agonist (EC50 ~ 740 nM).
InformationSpironolactone Spironolactone is a potent antagonist of the androgen receptor with IC50 of 77 nM.In vitroSpironolactone is a strong AR antagonist (IC50 ~ 77 nM), a weak GR antagonist (IC50 ~ 2.4 μM), and a weak PR agonist (EC50 ~ 740 nM).