BETRIXABAN (C005B-310010)

Catalog No.: C005B-310010
Manufacturer No.: SML2845-5MG
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Biochem/physiol Actions Betrixaban is an orally active, active site-targeting, highly potent and selective factor Xa (fXa) inhibitor (IC 50 = 1.5 nM: K i = 117 pM) with much reduced plasma kallikrein inhibitory activity (IC 50 = 6.

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Description
Specifications

Biochem/physiol Actions

Betrixaban is an orally active, active site-targeting, highly potent and selective factor Xa (fXa) inhibitor (IC₅₀ = 1.5 nM; K_i = 117 pM) with much reduced plasma kallikrein inhibitory activity (IC₅₀ = 6.3 μM) and little potency against thrombin, trypsin, t-PA, aPC or plasmin inhibition (IC₅₀ >10 μM). Betrixaban exhibits good pharmacokinetic properties and anticoagulant efficacy against various thromboembolism (VTE) events in vivo.

UPC:: 42262105
Condition:: New
HazmatClass:: No
MPN:: SML2845-5MG
CAS:: 330942-05-7

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